CD8A

CD8a molecule
OMIM: 186910, Gene2Phenotype

2 panels

Panel

Reviews

Mode of inheritance

Details

Green CD8A in COVID-19 research

Level 2: Viral research
Version 1.146

review

BIALLELIC, autosomal or pseudoautosomal

Sources

Expert Review Green
IUIS Classification February 2018
IUIS Classification December 2019
GRID V2.0
Victorian Clinical Genetics Services
ESID Registry 20171117
IUIS Classification December 2019
IUIS Classification February 2018
Victorian Clinical Genetics Services
ESID Registry 20171117
GRID V2.0

Phenotypes

Recurrent infections, may be asymptomatic
Susceptibility to respiratory infections associated with CD8alpha chain mutation
CD8 deficiency familial, 608957
Immunodeficiencies affecting cellular and humoral immunity

Amber CD8A in Primary immunodeficiency or monogenic inflammatory bowel disease

Level 2: Immunology
Version 8.78
Latest signed off version: v8.0 (30 Apr 2025)

review

BIALLELIC, autosomal or pseudoautosomal

Sources

Expert Review Amber
Other
IUIS Classification December 2019
IUIS Classification February 2018
Victorian Clinical Genetics Services
ESID Registry 20171117
GRID V2.0

Phenotypes

CD8 deficiency familial, 608957
Susceptibility to respiratory infections associated with CD8alpha chain mutation
Recurrent infections, may be asymptomatic
Immunodeficiencies affecting cellular and humoral immunity

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