CDCA7

cell division cycle associated 7
OMIM: 609937, Gene2Phenotype

2 panels

Panel	Reviews	Mode of inheritance	Details
Green CDCA7 in COVID-19 research Level 2: Viral research Version 1.146	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 Literature London North GLH NHS GMS North West GLH Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Expert Review Green Literature Phenotypes ICF recurrent respiratory infections ICF3 Immunodeficiency-centromeric instability-facial anomalies syndrome 3, 616910 immunodeficiency, centromeric instability, facial anomalies syndrome type 3 hypogammaglobulinaemia enteropathy Combined immunodeficiencies with associated or syndromic features Facial dysmorphic features, macroglossia, bacterial/opportunistic infections, malabsorption, cytopenias, malignancies, multiradial configurations of chromosomes 1, 9, 16 Immunodeficiency-centromeric instability-facial anomalies syndrome
Green CDCA7 in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.78 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH IUIS Classification February 2018 Expert Review Green Literature Phenotypes Immunodeficiency-centromeric instability-facial anomalies syndrome ICF Immunodeficiency-centromeric instability-facial anomalies syndrome 3, 616910 ICF3 immunodeficiency, centromeric instability, facial anomalies syndrome type 3 recurrent respiratory infections hypogammaglobulinaemia enteropathy Facial dysmorphic features, macroglossia, bacterial/opportunistic infections, malabsorption, cytopenias, malignancies, multiradial configurations of chromosomes 1, 9, 16 Combined immunodeficiencies with associated or syndromic features

Panel

Reviews

Mode of inheritance

Details

Green CDCA7 in COVID-19 research

Level 2: Viral research
Version 1.146

review

BIALLELIC, autosomal or pseudoautosomal

Sources

IUIS Classification February 2018
Literature
London North GLH
NHS GMS
North West GLH
Expert Review Green
NHS GMS
North West GLH
London North GLH
IUIS Classification February 2018
Expert Review Green
Literature

Phenotypes

ICF
recurrent respiratory infections
ICF3
Immunodeficiency-centromeric instability-facial anomalies syndrome 3, 616910
immunodeficiency, centromeric instability, facial anomalies syndrome type 3
hypogammaglobulinaemia
enteropathy
Combined immunodeficiencies with associated or syndromic features
Facial dysmorphic features, macroglossia, bacterial/opportunistic infections, malabsorption, cytopenias, malignancies, multiradial configurations of chromosomes 1, 9, 16
Immunodeficiency-centromeric instability-facial anomalies syndrome

Green CDCA7 in Primary immunodeficiency or monogenic inflammatory bowel disease

Level 2: Immunology
Version 8.78
Latest signed off version: v8.0 (30 Apr 2025)

review

BIALLELIC, autosomal or pseudoautosomal

Sources

NHS GMS
North West GLH
London North GLH
IUIS Classification February 2018
Expert Review Green
Literature

Phenotypes

Immunodeficiency-centromeric instability-facial anomalies syndrome
ICF
Immunodeficiency-centromeric instability-facial anomalies syndrome 3, 616910
ICF3
immunodeficiency, centromeric instability, facial anomalies syndrome type 3
recurrent respiratory infections
hypogammaglobulinaemia
enteropathy
Facial dysmorphic features, macroglossia, bacterial/opportunistic infections, malabsorption, cytopenias, malignancies, multiradial configurations of chromosomes 1, 9, 16
Combined immunodeficiencies with associated or syndromic features