CDCA7

cell division cycle associated 7
OMIM: 609937, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels

Green CDCA7 in COVID-19 research


Level 2: Viral research
Version 1.130

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • Literature
  • London North GLH
  • NHS GMS
  • North West GLH
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Expert Review Green
  • Literature
Phenotypes
  • ICF
  • recurrent respiratory infections
  • ICF3
  • Immunodeficiency-centromeric instability-facial anomalies syndrome 3, 616910
  • immunodeficiency, centromeric instability, facial anomalies syndrome type 3
  • hypogammaglobulinaemia
  • enteropathy
  • Combined immunodeficiencies with associated or syndromic features
  • Facial dysmorphic features, macroglossia, bacterial/opportunistic infections, malabsorption, cytopenias, malignancies, multiradial configurations of chromosomes 1, 9, 16
  • Immunodeficiency-centromeric instability-facial anomalies syndrome

Green CDCA7 in Primary immunodeficiency


Version 2.573
Latest signed off version: v2.1 (24 Feb 2020)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Expert Review Green
  • Literature
Phenotypes
  • Immunodeficiency-centromeric instability-facial anomalies syndrome
  • ICF
  • Immunodeficiency-centromeric instability-facial anomalies syndrome 3, 616910
  • ICF3
  • immunodeficiency, centromeric instability, facial anomalies syndrome type 3
  • recurrent respiratory infections
  • hypogammaglobulinaemia
  • enteropathy
  • Facial dysmorphic features, macroglossia, bacterial/opportunistic infections, malabsorption, cytopenias, malignancies, multiradial configurations of chromosomes 1, 9, 16
  • Combined immunodeficiencies with associated or syndromic features

Green CDCA7 in Severe Paediatric Disorders


Version 1.127

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Immunodeficiency-centromeric instability-facial anomalies syndrome 3, 616910