CDK16

cyclin dependent kinase 16
OMIM: 311550, Gene2Phenotype

6 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 6 panels
Amber CDK16 in Hereditary spastic paraplegia Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.311	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Amber Literature Phenotypes Intellectual disability and spastic paraplegia
Red CDK16 in Childhood onset hereditary spastic paraplegia Version 4.42 Latest signed off version: v4.0 (22 Mar 2023)	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Red Yorkshire and North East GLH NHS GMS London North GLH Literature Phenotypes Intellectual disability and spastic paraplegia, x-linked
Red CDK16 in Adult onset hereditary spastic paraplegia Version 3.21 Latest signed off version: v3.14 (31 Jul 2023)	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Yorkshire and North East GLH Expert Review Red NHS GMS London North GLH Phenotypes Intellectual disability and spastic paraplegia, x-linked
Red CDK16 in Adult onset neurodegenerative disorder Version 4.47 Latest signed off version: v4.34 (31 Jul 2023)	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Wessex and West Midlands GLH Yorkshire and North East GLH Expert Review Red London North GLH NHS GMS South West GLH Phenotypes Intellectual disability and spastic paraplegia
Red CDK16 in DDG2P Version 3.87 Latest signed off version: v3.1 (22 Mar 2023) Component of the following Super Panels: Paediatric disorders	review	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	Sources DD-Gene2Phenotype Expert Review Red Phenotypes INTELLECTUAL DISABILITY
Amber CDK16 in Intellectual disability - microarray and sequencing Level 3: Neurodevelopmental disorders Level 2: Neurology and neurodevelopmental disorders Version 5.532 Latest signed off version: v5.0 (22 Mar 2023) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Sources Expert Review Amber Emory Genetics Laboratory Phenotypes Intellectual disability, MONDO:0001071 Tags Q4_23_promote_green Q4_23_NHS_review