1. Genes and Genomic Entities
  2. CFHR4

CFHR4

complement factor H related 4
OMIM: 605337, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Green CFHR4 in COVID-19 research


Level 2: Viral research
Version 1.147

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • IUIS Classification February 2018
  • IUIS Classification December 2019
  • GRID V2.0
  • Victorian Clinical Genetics Services
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • GRID V2.0
Phenotypes
  • Complement Deficiencies
  • Age related macular degeneration
  • Atypical hemolytic uremic syndrome susceptibility
  • Older onset atypical hemolytic-uremic syndrome, disseminated neisserial infections
Red CFHR4 in Atypical haemolytic uraemic syndrome


Level 2: Renal
Version 3.8
Latest signed off version: v3.6 (30 Apr 2025)

Component of the following Super Panels:

  • Unexplained young onset end-stage renal disease

    		•  review Unknown
    Sources
    • Other
    Phenotypes
    • Age related macular degeneration
    • Atypical hemolytic uremic syndrome susceptibility
    Red CFHR4 in Primary immunodeficiency or monogenic inflammatory bowel disease


    Level 2: Immunology
    Version 8.85
    Latest signed off version: v8.0 (30 Apr 2025)

    		review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    • IUIS Classification December 2019
    • IUIS Classification February 2018
    • Victorian Clinical Genetics Services
    • GRID V2.0
    Phenotypes
    • Older onset atypical hemolytic-uremic syndrome, disseminated neisserial infections
    • Age related macular degeneration
    • Complement Deficiencies
    • Atypical hemolytic uremic syndrome susceptibility