1. Genes and Genomic Entities
  2. CIITA

CIITA

class II major histocompatibility complex transactivator
OMIM: 600005, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green CIITA in COVID-19 research


Level 2: Viral research
Version 1.147

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • London North GLH
  • GOSH PID v.8.0
  • NHS GMS
  • GRID V2.0
  • Victorian Clinical Genetics Services
  • North West GLH
  • ESID Registry 20171117
  • Combined B and T cell defect v1.12
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • ESID Registry 20171117
  • GRID V2.0
  • GOSH PID v.8.0
  • Combined B and T cell defect v1.12
Phenotypes
  • HLA class II deficiency
  • Combined immunodeficiency (MHC class II deficiency, bare lymphocyte syndrome)
  • Immunodeficiencies affecting cellular and humoral immunity
  • Respiratory and gastrointestinal infections, liver/biliary tract disease
  • Bare lymphocyte syndrome, type II, complementation group A
Green CIITA in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 9.24
Latest signed off version: v9.0 (6 May 2026)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Other
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
  • GOSH PID v.8.0
  • Combined B and T cell defect v1.12
Phenotypes
  • Bare lymphocyte syndrome, type II, complementation group A
  • Combined immunodeficiency (MHC class II deficiency, bare lymphocyte syndrome)
  • HLA class II deficiency
  • Respiratory and gastrointestinal infections, liver/biliary tract disease
  • Immunodeficiencies affecting cellular and humoral immunity