1. Genes and Genomic Entities
  2. CTR9

CTR9

CTR9 homolog, Paf1/RNA polymerase II complex component
OMIM: 609366, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Green CTR9 in Childhood solid tumours


Level 2: Cancer susceptibility
Version 5.9
Latest signed off version: v5.0 (30 Apr 2025)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert list
  • Expert Review Green
Phenotypes
  • Familial Wilms tumor
Tags
  • gene-checked
Green CTR9 in DDG2P


Version 6.424
Latest signed off version: v6.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • CTR9-related neurodevelopmental disorder
    Tags
    • de novo
    • gene-checked
    Green CTR9 in Intellectual disability


    Level 2: Developmental disorders
    Version 9.285
    Latest signed off version: v9.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • NHS GMS
    • Literature
    Phenotypes
    • Macrocephaly, HP:0000256
    • Motor delay, HP:0001270
    • intellectual disability, MONDO:0001071
    • Delayed speech and language development
    • Behavioral abnormality
    • Autistic behavior
    • Failure to thrive
    • Feeding difficulties
    • Abnormality of the cardiovascular system
    Tags
    • gene-checked
    Green CTR9 in Wilms tumour with features suggestive of predisposition


    Level 2: Inherited cancer
    Version 1.4
    Latest signed off version: v1.0 (30 Nov 2022)

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    Phenotypes
    • Familial Wilms tumor
    Tags
    • gene-checked