1. Genes and Genomic Entities
  2. DNAJB2

DNAJB2

DnaJ heat shock protein family (Hsp40) member B2
OMIM: 604139, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Green DNAJB2 in Adult onset neurodegenerative disorder


Level 2: Neurology
Version 8.11
Latest signed off version: v8.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • NHS GMS
  • Expert list
Phenotypes
  • Spinal muscular atrophy, distal, autosomal recessive, 5, OMIM:614881
  • young adult-onset distal hereditary motor neuropathy, MONDO:0013947
Red DNAJB2 in Paediatric motor neuronopathies


Level 2: Neurology
Version 3.12
Latest signed off version: v3.9 (30 Apr 2025)

Component of the following Super Panels:

  • Hypotonic infant
  • Other rare neuromuscular disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    • Expert
    • Radboud University Medical Center, Nijmegen
    Phenotypes
    • Spinal muscular atrophy, distal, autosomal recessive, 5, 614881
    Green DNAJB2 in Hereditary neuropathy

    Level 3: Motor and Sensory Disorders of the PNS
    Level 2: Neurology and neurodevelopmental disorders
    Version 1.506

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • South West GLH
    • NHS GMS
    • London North GLH
    • Emory Genetics Laboratory
    • Expert list
    Phenotypes
    • Hereditary Neuropathies
    Green DNAJB2 in Hereditary neuropathy or pain disorder


    Level 2: Neurology
    Version 7.36
    Latest signed off version: v7.0 (30 Apr 2025)

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • South West GLH
    • Emory Genetics Laboratory
    • Expert list
    • London North GLH
    • NHS GMS
    • South West GLH
    • NHS GMS
    • London North GLH
    Phenotypes
    • Hereditary Neuropathies