DNASE2

deoxyribonuclease 2, lysosomal
OMIM: 126350, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels

Green DNASE2 in COVID-19 research


Level 2: Viral research
Version 1.80

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • London North GLH
  • NHS GMS
  • North West GLH
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • Expert Review Green
  • IUIS Classification February 2018
Phenotypes
  • liver fibrosis
  • multisystem autoinflammatory syndrome
  • SLE
  • severe neonatal anemia
  • Autoinflammatory Disorders
  • deforming arthropathy
  • Glomerulonephritis, arthropathy, vasculitis
  • membranoproliferative glomerulonephritis

Green DNASE2 in Primary immunodeficiency


Version 2.478
Latest signed off version: v2.1 (24 Feb 2020)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • North West GLH
  • London North GLH
  • Expert Review Green
  • IUIS Classification February 2018
Phenotypes
  • Glomerulonephritis, arthropathy, vasculitis
  • Autoinflammatory Disorders
  • multisystem autoinflammatory syndrome
  • severe neonatal anemia
  • membranoproliferative glomerulonephritis
  • liver fibrosis
  • deforming arthropathy
  • SLE

Green DNASE2 in Severe Paediatric Disorders


Version 1.84

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Rheumatoid arthritis