DOCK2

dedicator of cytokinesis 2
OMIM: 603122, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Green DOCK2 in COVID-19 research


Level 2: Viral research
Version 1.141

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • London North GLH
  • NHS GMS
  • GRID V2.0
  • North West GLH
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • GRID V2.0
Phenotypes
  • Dock 2 deficiency, Immunodeficiency 40
  • Immunodeficiencies affecting cellular and humoral immunity
  • Immunodeficiency 40, 616433
  • Nl NK cells, but defective function. Poor interferon responses in hematopoietic and non-hematopoietic cells
Green DOCK2 in Primary immunodeficiency or monogenic inflammatory bowel disease


Version 4.191
Latest signed off version: v4.0 (22 Mar 2023)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Other
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • GRID V2.0
Phenotypes
  • Dock 2 deficiency, Immunodeficiency 40
  • Immunodeficiency 40, 616433
  • Nl NK cells, but defective function. Poor interferon responses in hematopoietic and non-hematopoietic cells
  • Immunodeficiencies affecting cellular and humoral immunity
Green DOCK2 in Severe Paediatric Disorders


Version 1.182

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Immunodeficiency 40, 616433