DUOX2

dual oxidase 2
OMIM: 606759, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
No list DUOX2 in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 9.18
Latest signed off version: v9.0 (6 May 2026)

review Unknown
Sources
  • Literature
Phenotypes
  • Inflammatory bowel disease
  • IBD
  • VEOIBD
Green DUOX2 in Congenital hypothyroidism


Level 2: Endocrinology
Version 3.10
Latest signed off version: v3.3 (6 May 2026)

review BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Eligibility statement prior genetic testing
  • UKGTN
  • Illumina TruGenome Clinical Sequencing Services
Phenotypes
  • Congenital hypothyroidism
  • Thryoid dyshormonogenesis 6, 607200
  • permanent congenital hypothyroidism
  • transient congenital hypothyroidism
  • eutopic gland-in-situ
  • goitre
  • borderline congenital hypothyroidism
  • iodide organification defect
Tags
  • monogenic-polygenic