DUOX2

3 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 3 panels
Red DUOX2 in Intestinal failure or congenital diarrhoea Level 2: Gastrohepatology Version 3.17 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red Literature Phenotypes inflammatory bowel disease, MONDO:0005265
Amber DUOX2 in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 9.37 Latest signed off version: v9.0 (6 May 2026)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Literature Phenotypes inflammatory bowel disease MONDO:0005265 IBD VEOIBD Tags watchlist_moi Q3_26_promote_green
Green DUOX2 in Congenital hypothyroidism Level 2: Endocrinology Version 3.10 Latest signed off version: v3.3 (6 May 2026)	review	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Sources Expert Review Green Eligibility statement prior genetic testing UKGTN Illumina TruGenome Clinical Sequencing Services Phenotypes Congenital hypothyroidism Thryoid dyshormonogenesis 6, 607200 permanent congenital hypothyroidism transient congenital hypothyroidism eutopic gland-in-situ goitre borderline congenital hypothyroidism iodide organification defect Tags monogenic-polygenic