F11

coagulation factor XI
OMIM: 264900, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels

Green F11 in Inherited bleeding disorders

Level 3: Haemostasis disorders
Level 2: Haematological and immunological disorders
Version 1.159

review BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • BRIDGE Study Tier 1 Gene
Phenotypes
  • Factor XI deficiency

Green F11 in Bleeding and platelet disorders


Version 1.26
Latest signed off version: v1.2 (3 Mar 2020)

review BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Sources
  • North West GLH
  • Yorkshire and North East GLH
  • London South GLH
  • NHS GMS
  • Expert Review Green
  • Wessex and West Midlands GLH
Phenotypes
  • 612416 Factor XI deficiency

Green F11 in Severe Paediatric Disorders


Version 1.76

review BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Factor XI deficiency, autosomal recessive, 612416
  • Factor XI deficiency, autosomal dominant, 612416