F12

coagulation factor XII
OMIM: 610619, Gene2Phenotype

6 panels

Panel Reviews Mode of inheritance Details
6 panels

Green F12 in COVID-19 research


Level 2: Viral research
Version 1.130

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • London North GLH
  • NHS GMS
  • GRID V2.0
  • North West GLH
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • Expert Review Green
  • Victorian Clinical Genetics Services
  • GRID V2.0
Phenotypes
  • Angioedema, hereditary, 3, OMIM:610618

Green F12 in Inherited bleeding disorders

Level 3: Haemostasis disorders
Level 2: Haematological and immunological disorders
Version 1.172

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • BRIDGE Study Tier 1 Gene
Phenotypes
  • Angioedema, hereditary, type III, OMIM:610618
  • Factor XII deficiency, OMIM:234000
Tags
  • watchlist_moi

Green F12 in Primary immunodeficiency


Version 2.572
Latest signed off version: v2.1 (24 Feb 2020)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • NHS GMS
  • North West GLH
  • London North GLH
  • Expert Review Green
  • Victorian Clinical Genetics Services
  • GRID V2.0
Phenotypes
  • Angioedema, hereditary, 3, OMIM:610618

Green F12 in Vascular skin disorders


Version 1.49
Latest signed off version: v1.3 (15 Oct 2020)

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • London North GLH
  • NHS GMS
  • Expert Review Green
Phenotypes
  • Angioedema, hereditary, type III, OMIM:610618
  • Factor XII deficiency, OMIM:234000
Tags
  • Q2_22_MOI
  • Q2_22_expert_review

Green F12 in Bleeding and platelet disorders


Version 1.43
Latest signed off version: v1.2 (3 Mar 2020)

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • North West GLH
  • Yorkshire and North East GLH
  • London South GLH
  • NHS GMS
  • Expert Review Green
  • Wessex and West Midlands GLH
Phenotypes
  • Angioedema, hereditary, type III, OMIM:610618
  • Factor XII deficiency, OMIM:234000
Tags
  • Q2_22_MOI
  • Q2_22_phenotype
  • Q2_22_expert_review

Green F12 in Severe Paediatric Disorders


Version 1.127

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Angioedema, hereditary, 3, OMIM:610618
  • Factor XII deficiency, OMIM:234000