F8

coagulation factor VIII
OMIM: 300841, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Green F8 in Inherited bleeding disorders

Level 3: Haemostasis disorders
Level 2: Haematological and immunological disorders
Version 1.182

review X-LINKED: hemizygous mutation in males, biallelic mutations in females
Sources
  • Expert Review Green
  • BRIDGE Study Tier 1 Gene
Phenotypes
  • Haemophilia A
Tags
  • non-coding-known-pathogenic
  • gene-therapy-trial
Green F8 in Bleeding and platelet disorders


Level 2: Haematology
Version 4.6
Latest signed off version: v4.0 (30 Apr 2025)

review X-LINKED: hemizygous mutation in males, biallelic mutations in females
Sources
  • North West GLH
  • Yorkshire and North East GLH
  • London South GLH
  • NHS GMS
  • Expert Review Green
  • Wessex and West Midlands GLH
Phenotypes
  • 306700 Haemophilia A
Green F8 in Factor VIII deficiency


Level 2: Haematology
Version 1.3
Latest signed off version: v1.0 (14 Sep 2023)

review X-LINKED: hemizygous mutation in males, biallelic mutations in females
Sources
  • NHS GMS
  • Expert Review Green
Phenotypes
  • Hemophilia A, OMIM:306700
  • hemophilia A, MONDO:0010602