1. Genes and Genomic Entities
  2. FAM177A1

FAM177A1

family with sequence similarity 177 member A1
Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Amber FAM177A1 in Fetal anomalies


Level 2: Fetal (including NIPD)
Version 8.1
Latest signed off version: v8.0 (12 Aug 2026)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
Phenotypes
  • Neurodevelopmental disorder with white matter abnormalities and gait disturbance, OMIM:621152
Tags
  • gene-checked
Green FAM177A1 in DDG2P


Version 8.1
Latest signed off version: v8.0 (12 Aug 2026)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • FAM177A1-related neurodevelopmental disorder with macrocephaly
    • MONDO:0100038
    • Neurodevelopmental disorder with white matter abnormalities and gait disturbance, OMIM:621152
    Tags
    • gene-checked
    Green FAM177A1 in Intellectual disability


    Level 2: Developmental disorders
    Version 11.1
    Latest signed off version: v11.0 (12 Aug 2026)

    Component of the following Super Panels:

  • Hypotonic infant
  • Leukodystrophy, childhood onset
  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    • Literature
    Phenotypes
    • Neurodevelopmental disorder with white matter abnormalities and gait disturbance, OMIM:621152
    Tags
    • gene-checked