FAT4

FAT atypical cadherin 4
OMIM: 612411, Gene2Phenotype

8 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 8 panels
Green FAT4 in COVID-19 research Level 2: Viral research Version 1.146	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH NHS GMS North West GLH Victorian Clinical Genetics Services Expert Review Green NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services Phenotypes Lymphangiectasia and lymphedema with facial abnormalities and other dysmorphic features Combined immunodeficiencies with associated or syndromic features Hennekam lymphangiectasia-lymphedema syndrome 2, 616006
Green FAT4 in Intestinal failure or congenital diarrhoea Level 2: Gastrohepatology Version 3.7 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Phenotypes Hennekam lymphangiectasia-lymphedema syndrome 2, OMIM:616006
Amber FAT4 in Malformations of cortical development Level 2: Neurology Version 7.30 Latest signed off version: v7.0 (30 Oct 2024) Component of the following Super Panels: Cerebral malformation	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Expert list Phenotypes Van Maldergem syndrome 2, OMIM:615546 Tags watchlist
Green FAT4 in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.78 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Phenotypes Hennekam lymphangiectasia-lymphedema syndrome 2, 616006 Lymphangiectasia and lymphedema with facial abnormalities and other dysmorphic features Combined immunodeficiencies with associated or syndromic features
Green FAT4 in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.140 Latest signed off version: v6.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources PAGE DD-Gene2Phenotype Expert Review Green Phenotypes PERIVENTRICULAR NEURONAL HETEROTOPIA
Green FAT4 in DDG2P Version 6.424 Latest signed off version: v6.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources DD-Gene2Phenotype Expert Review Green Phenotypes PERIVENTRICULAR NEURONAL HETEROTOPIA HENNEKAM LYMPHANGIECTASIA-LYMPHEDEMA SYNDROME 2 616006 VAN MALDERGEM SYNDROME 615546
Green FAT4 in Intellectual disability Level 2: Developmental disorders Version 9.285 Latest signed off version: v9.0 (30 Apr 2025) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Phenotypes PERIVENTRICULAR NEURONAL HETEROTOPIA
Green FAT4 in Primary lymphoedema Level 2: Cardiology Version 4.21 Latest signed off version: v4.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources London South GLH Expert Review Green Radboud University Medical Center, Nijmegen Phenotypes Hennekam lymphangiectasia-lymphedema syndrome 2, 616006 Van Maldergem syndrome 2, 615546