FAT4

FAT atypical cadherin 4
OMIM: 612411, Gene2Phenotype

9 panels

Panel Reviews Mode of inheritance Details
9 panels

Green FAT4 in COVID-19 research


Level 2: Viral research
Version 1.130

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • London North GLH
  • NHS GMS
  • North West GLH
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • Expert Review Green
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
Phenotypes
  • Lymphangiectasia and lymphedema with facial abnormalities and other dysmorphic features
  • Combined immunodeficiencies with associated or syndromic features
  • Hennekam lymphangiectasia-lymphedema syndrome 2, 616006

Green FAT4 in Intestinal failure


Version 1.48
Latest signed off version: v1.2 (4 Mar 2020)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
Phenotypes
  • Hennekam lymphangiectasia-lymphedema syndrome 2, OMIM:616006

Amber FAT4 in Malformations of cortical development

Level 3: Neurodevelopmental disorders
Level 2: Neurology and neurodevelopmental disorders
Version 2.148
Latest signed off version: v2.2 (25 Feb 2020)

Component of the following Super Panels:

  • Cerebral malformations
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Amber
    • Expert list
    Phenotypes
    • Van Maldergem syndrome 2, OMIM:615546
    Tags
    • watchlist

    Green FAT4 in Primary immunodeficiency


    Version 2.573
    Latest signed off version: v2.1 (24 Feb 2020)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Other
    • NHS GMS
    • North West GLH
    • London North GLH
    • IUIS Classification February 2018
    • Victorian Clinical Genetics Services
    Phenotypes
    • Hennekam lymphangiectasia-lymphedema syndrome 2, 616006
    • Lymphangiectasia and lymphedema with facial abnormalities and other dysmorphic features
    • Combined immunodeficiencies with associated or syndromic features

    Green FAT4 in Fetal anomalies


    Version 1.900
    Latest signed off version: v1.92 (21 Aug 2020)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • PAGE DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • PERIVENTRICULAR NEURONAL HETEROTOPIA

    Green FAT4 in DDG2P


    Version 2.78
    Latest signed off version: v2.2 (13 Feb 2020)

    Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • PERIVENTRICULAR NEURONAL HETEROTOPIA
    • HENNEKAM LYMPHANGIECTASIA-LYMPHEDEMA SYNDROME 2 616006
    • VAN MALDERGEM SYNDROME 615546

    Green FAT4 in Intellectual disability

    Level 3: Neurodevelopmental disorders
    Level 2: Neurology and neurodevelopmental disorders
    Version 3.1676
    Latest signed off version: v3.2 (13 Feb 2020)

    Component of the following Super Panels:

  • Hypotonic infant
  • Paediatric disorders
  • White matter disorders - childhood onset
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    Phenotypes
    • PERIVENTRICULAR NEURONAL HETEROTOPIA

    Green FAT4 in Primary lymphoedema

    Level 3: Lymphatic Disorders
    Level 2: Cardiovascular disorders
    Version 2.25
    Latest signed off version: v2.2 (2 Mar 2020)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • London South GLH
    • Expert Review Green
    • Radboud University Medical Center, Nijmegen
    Phenotypes
    • Hennekam lymphangiectasia-lymphedema syndrome 2, 616006
    • Van Maldergem syndrome 2, 615546

    Green FAT4 in Severe Paediatric Disorders


    Version 1.127

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Next Generation Children Project
    • Expert Review Green
    • Expert list
    Phenotypes
    • Hennekam lymphangiectasia-lymphedema syndrome 2, 616006
    • Van Maldergem syndrome 2, 615546