1. Genes and Genomic Entities
  2. FBXW11

FBXW11

F-box and WD repeat domain containing 11
OMIM: 605651, Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels
Green FBXW11 in Limb disorders


Level 2: Musculoskeletal
Version 7.22
Latest signed off version: v7.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Green
    • NHS GMS
    • Literature
    Phenotypes
    • Neurodevelopmental, jaw, eye, and digital syndrome, OMIM:618914
    • neurodevelopmental, jaw, eye, and digital syndrome, MONDO:0030057
    Green FBXW11 in Skeletal dysplasia


    Level 2: Musculoskeletal
    Version 8.38
    Latest signed off version: v8.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Green
    • NHS GMS
    • Literature
    Phenotypes
    • Neurodevelopmental, jaw, eye, and digital syndrome, OMIM:618914
    • neurodevelopmental, jaw, eye, and digital syndrome, MONDO:0030057
    Amber FBXW11 in Fetal anomalies


    Level 2: Fetal (including NIPD)
    Version 6.181
    Latest signed off version: v6.0 (30 Apr 2025)

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • NHS GMS
    • Expert Review Amber
    Phenotypes
    • Neurodevelopmental, jaw, eye, and digital syndrome, OMIM:618914
    • Neurodevelopmental, jaw, eye, and digital syndrome
    Green FBXW11 in DDG2P


    Version 6.447
    Latest signed off version: v6.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Green
    • DD-Gene2Phenotype
    Phenotypes
    • SYNDROMIC INTELLECTUAL DISABILITY 612100
    Green FBXW11 in Intellectual disability


    Level 2: Developmental disorders
    Version 9.345
    Latest signed off version: v9.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Neurodevelopmental, jaw, eye, and digital syndrome, OMIM:618914
    • neurodevelopmental, jaw, eye, and digital syndrome, MONDO:003005