1. Genes and Genomic Entities
  2. FCGR3A

FCGR3A

Fc fragment of IgG receptor IIIa
OMIM: 146740, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green FCGR3A in COVID-19 research


Level 2: Viral research
Version 1.146

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
  • Melbourne Genomics Health Alliance Immunology Flagship
  • IUIS Classification December 2019
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • severe herpes viral infections, particularly VZV, Epstein Barr virus (EBV), and (HPV)
  • CD16 deficiency
  • predisposition to severe viral infection
  • Immunodeficiency 20, 615707
  • Autosomal recessive primary immunodeficiency with defective spontaneous NK cell cytotoxicity
  • Defects in Intrinsic and Innate Immunity
  • Fc receptor deficiencies
Amber FCGR3A in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 8.78
Latest signed off version: v8.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification December 2019
  • Expert Review Amber
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • Immunodeficiency 20, 615707
  • CD16 deficiency
  • Defects in Intrinsic and Innate Immunity
  • Fc receptor deficiencies
  • predisposition to severe viral infection
  • severe herpes viral infections, particularly VZV, Epstein Barr virus (EBV), and (HPV)
  • Autosomal recessive primary immunodeficiency with defective spontaneous NK cell cytotoxicity
Tags
  • watchlist