FGG

fibrinogen gamma chain
OMIM: 134850, Gene2Phenotype

4 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 4 panels
Green FGG in Inherited bleeding disorders Level 3: Haemostasis disorders Level 2: Haematological and immunological disorders Version 1.182	review	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Sources Other Radboud University Medical Center, Nijmegen Expert Review Green BRIDGE Study Tier 1 Gene Phenotypes Fibrinogen deficiency Dysfibrinogenemia,congenital,616004 Dysfibrinogenemia, congenita Hypodysfibrinogenemia
Green FGG in Thrombophilia with a likely monogenic cause Level 2: Haematology Version 2.10 Latest signed off version: v2.2 (22 Mar 2023)	review	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Sources North West GLH Yorkshire and North East GLH London South GLH NHS GMS Expert Review Green Wessex and West Midlands GLH Phenotypes Afibrinogenemia, congenital, OMIM:202400 Hypofibrinogenemia, congenital, OMIM:202400 Dysfibrinogenemia, congenital, OMIM:616004 Hypodysfibrinogenemia, OMIM:616004 Thrombophilia, MONDO:0002305
Green FGG in Bleeding and platelet disorders Level 2: Haematology Version 4.6 Latest signed off version: v4.0 (30 Apr 2025)	review	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Sources North West GLH Yorkshire and North East GLH London South GLH NHS GMS Expert Review Green Wessex and West Midlands GLH Phenotypes 202400 Afibrinogenemia, congenital 616004 Hypodysfibrinogenemia, congenital 616004 Dysfibrinogenemia, congenital
Red FGG in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.140 Latest signed off version: v6.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red Phenotypes Afibrinogenemia, congenital Hypofibrinogenemia, congenital