FICD

FIC domain containing
Gene2Phenotype

6 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 6 panels
Amber FICD in Neonatal diabetes Level 2: Endocrinology Version 5.17 Latest signed off version: v5.0 (7 Aug 2024)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Expert review Phenotypes Neonatal diabetes Neonatal insulin-dependent diabetes mellitus, HP:0000857 severe neurodevelopmental delay, HP:0012758 skeletal abnormalities Tags watchlist
Amber FICD in Monogenic diabetes Level 2: Endocrinology Version 3.8 Latest signed off version: v3.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Literature Phenotypes Spastic paraplegia 92, autosomal recessive, OMIM:620911 diabetes mellitus, MONDO:0005015 Neonatal insulin-dependent diabetes mellitus, HP:0000857 Tags Q3_25_promote_green recurrent-variant
Green FICD in Childhood onset hereditary spastic paraplegia Level 2: Neurology Version 8.30 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green Literature Phenotypes Spastic paraplegia 92, autosomal recessive, OMIM:620911 Tags gene-checked recurrent-variant
Red FICD in DDG2P Version 6.424 Latest signed off version: v6.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources DD-Gene2Phenotype Expert Review Red Phenotypes FICD-related infancy-onset diabetes and neurodevelopmental disorder
Amber FICD in Intellectual disability Level 2: Developmental disorders Version 9.279 Latest signed off version: v9.0 (30 Apr 2025) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Expert review Phenotypes Neonatal diabetes Neonatal insulin-dependent diabetes mellitus, HP:0000857 severe neurodevelopmental delay, HP:0012758 skeletal abnormalities. Tags watchlist
Green FICD in Hereditary neuropathy or pain disorder Level 2: Neurology Version 7.36 Latest signed off version: v7.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Literature Phenotypes Spastic paraplegia 92, autosomal recessive, OMIM:620911 Tags gene-checked