FLI1

Fli-1 proto-oncogene, ETS transcription factor
OMIM: 193067, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels

Green FLI1 in Inherited bleeding disorders

Level 3: Haemostasis disorders
Level 2: Haematological and immunological disorders
Version 1.156

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • BRIDGE Study Tier 1 Gene
Phenotypes
  • Paris-Trousseau thrombocytopenia and Jacobson syndrome (BIALLELIC, autosomal or pseudoautosomal)
  • Bleeding disorder, platelet-type, 21
  • 617443
  • BDPLT21
  • BDPLT21, Storage Pool Disorder and Bleeding (MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown)
  • BDPLT21, Paris Trousseau like (BIALLELIC, autosomal or pseudoautosomal)
  • Bleeding disorder, platelet-type, 21

Green FLI1 in Bleeding and platelet disorders


Version 1.4
Signed off v.1.2 on 3 Mar 2020

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • North West GLH
  • Yorkshire and North East GLH
  • London South GLH
  • NHS GMS
  • Expert Review Green
  • Wessex and West Midlands GLH
Phenotypes
  • 617443 BLEEDING DISORDER, PLATELET-TYPE, 21
  • BDPLT21
  • 617443.BLEEDING DISORDER, PLATELET-TYPE, 21

Amber FLI1 in Cytopenia - NOT Fanconi anaemia


Version 1.6
Signed off v.1.2 on 3 Mar 2020

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • Expert review Amber
  • NHS GMS
  • North West GLH
  • London South GLH
  • Yorkshire and North East GLH
  • Wessex and West Midlands GLH
Phenotypes
  • Bleeding disorder, platelet-type, 21, 617443

Green FLI1 in Severe Paediatric Disorders


Version 1.6

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Bleeding disorder, platelet-type, 21, 617443