1. Genes and Genomic Entities
  2. FLI1

FLI1

Fli-1 proto-oncogene, ETS transcription factor
OMIM: 193067, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Green FLI1 in Inherited bleeding disorders

Level 3: Haemostasis disorders
Level 2: Haematological and immunological disorders
Version 1.182

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • BRIDGE Study Tier 1 Gene
Phenotypes
  • Paris-Trousseau thrombocytopenia and Jacobson syndrome (BIALLELIC, autosomal or pseudoautosomal)
  • Bleeding disorder, platelet-type, 21
  • 617443
  • BDPLT21
  • BDPLT21, Storage Pool Disorder and Bleeding (MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown)
  • BDPLT21, Paris Trousseau like (BIALLELIC, autosomal or pseudoautosomal)
  • Bleeding disorder, platelet-type, 21
Green FLI1 in Bleeding and platelet disorders


Level 2: Haematology
Version 4.6
Latest signed off version: v4.0 (30 Apr 2025)

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • North West GLH
  • Yorkshire and North East GLH
  • London South GLH
  • NHS GMS
  • Expert Review Green
  • Wessex and West Midlands GLH
Phenotypes
  • 617443 BLEEDING DISORDER, PLATELET-TYPE, 21
  • BDPLT21
  • 617443.BLEEDING DISORDER, PLATELET-TYPE, 21
Amber FLI1 in Cytopenia - NOT Fanconi anaemia


Level 2: Haematology
Version 4.32
Latest signed off version: v4.0 (30 Apr 2025)

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • Expert review Amber
  • NHS GMS
  • North West GLH
  • London South GLH
  • Yorkshire and North East GLH
  • Wessex and West Midlands GLH
Phenotypes
  • Bleeding disorder, platelet-type, 21, 617443