1. Genes and Genomic Entities
  2. FN1

FN1

fibronectin 1
OMIM: 135600, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Green FN1 in Skeletal dysplasia


Level 2: Musculoskeletal
Version 10.5
Latest signed off version: v10.0 (12 Aug 2026)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • NHS GMS
    Phenotypes
    • Spondylometaphyseal dysplasia, corner fracture type 184255
    Green FN1 in Fetal anomalies


    Level 2: Fetal (including NIPD)
    Version 8.5
    Latest signed off version: v8.0 (12 Aug 2026)

    		review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Green
    • NHS GMS
    • PAGE DD-Gene2Phenotype
    Phenotypes
    • Spondylometaphyseal dysplasia, corner fracture type, OMIM:184255
    Green FN1 in DDG2P


    Version 8.1
    Latest signed off version: v8.0 (12 Aug 2026)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Green
    • DD-Gene2Phenotype
    Phenotypes
    • Spondylometaphyseal Dysplasia with Corner Fractures 184255
    Green FN1 in Proteinuric renal disease


    Level 2: Renal
    Version 6.18
    Latest signed off version: v6.13 (12 Aug 2026)

    Component of the following Super Panels:

  • Unexplained young onset end-stage renal disease

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Glomerulopathy with fibronectin deposits 2, OMIM:601894