1. Genes and Genomic Entities
  2. GDF11

GDF11

growth differentiation factor 11
OMIM: 603936, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Red GDF11 in Currarino triad


Version 1.2

review Unknown
Sources
  • Other
Phenotypes
  • anteroposterior patterning defects, renal and palatal agenesis, presacral mass, anorectal malformation, and exomphalos
Green GDF11 in Fetal anomalies


Level 2: Fetal (including NIPD)
Version 6.140
Latest signed off version: v6.0 (30 Apr 2025)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • NHS GMS
Phenotypes
  • ?Vertebral hypersegmentation and orofacial anomalies, OMIM:619122
Green GDF11 in DDG2P


Version 6.424
Latest signed off version: v6.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • GDF11-related vertebral hypersegmentation, orofacial anomalies and neurodevelopmental disorder, OMIM:619122
    Green GDF11 in Clefting


    Level 2: Musculoskeletal
    Version 6.20
    Latest signed off version: v6.5 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • NHS GMS
    • Literature
    Phenotypes
    • Vertebral hypersegmentation and orofacial anomalies (VHO), OMIM:619122