GRM6

Red GRM6 in Glaucoma (developmental)

Level 3: Anterior segment abnormalities
Level 2: Ophthalmological disorders
Version 1.42

Sources

• NHS GMS
• Emory Genetics Laboratory

Phenotypes

• Eye Disorders

Red GRM6 in Fetal anomalies

Version 1.905
Latest signed off version: v1.92 (21 Aug 2020)

Sources

• Expert Review Red
• PAGE DD-Gene2Phenotype

Phenotypes

• NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B

Green GRM6 in DDG2P

Version 2.78
Latest signed off version: v2.2 (13 Feb 2020)

Component of the following Super Panels:

Sources

• DD-Gene2Phenotype
• Expert Review Green

Phenotypes

• NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B 257270

Red GRM6 in Intellectual disability

Level 3: Neurodevelopmental disorders
Level 2: Neurology and neurodevelopmental disorders
Version 3.1677
Latest signed off version: v3.2 (13 Feb 2020)

Component of the following Super Panels:

Sources

• Expert Review Red
• BRIDGE study SPEED NEURO Tier1 Gene

Phenotypes

• Night blindness, congenital stationary (complete), 1B, autosomal
• recessive, 257270

Green GRM6 in Retinal disorders

Level 3: Posterior segment abnormalities
Level 2: Ophthalmological disorders
Version 2.285
Latest signed off version: v2.195 (5 Aug 2021)

Sources

• NHS GMS
• Expert Review Green

Phenotypes

• Congenital Stationary Night Blindness
• Night blindness, congenital stationary (complete), 1B, autosomal recessive, 257270

Red GRM6 in Structural eye disease

Version 1.132
Latest signed off version: v1.3 (4 Mar 2020)

Sources

• NHS GMS
• Expert Review Red

Phenotypes

• Night blindness, congenital stationary (complete), 1B, autosomal recessive, 257270
• Eye Disorders

Green GRM6 in Severe Paediatric Disorders

Version 1.127

Sources

• Next Generation Children Project
• Expert Review Green
• Expert list

Phenotypes

• Night blindness, congenital stationary (complete), 1B, autosomal recessive, 257270