1. Genes and Genomic Entities
  2. HELLS

HELLS

helicase, lymphoid specific
OMIM: 603946, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green HELLS in COVID-19 research


Level 2: Viral research
Version 1.147

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • Literature
  • London North GLH
  • NHS GMS
  • North West GLH
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Expert Review Green
  • Literature
Phenotypes
  • ICF
  • Immunodeficiency-centromeric instability-facial anomalies syndrome 4, 616911
  • ICF4
  • Combined immunodeficiencies with associated or syndromic features
  • Facial dysmorphic features, macroglossia, bacterial/opportunistic infections, malabsorption, cytopenias, malignancies, multiradial configurations of chromosomes 1, 9, 16
  • Immunodeficiency-centromeric instability-facial anomalies syndrome
Green HELLS in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 9.18
Latest signed off version: v9.0 (6 May 2026)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Expert Review Green
  • Literature
Phenotypes
  • Immunodeficiency-centromeric instability-facial anomalies syndrome
  • ICF
  • Immunodeficiency-centromeric instability-facial anomalies syndrome 4, 616911
  • ICF4
  • Facial dysmorphic features, macroglossia, bacterial/opportunistic infections, malabsorption, cytopenias, malignancies, multiradial configurations of chromosomes 1, 9, 16
  • Combined immunodeficiencies with associated or syndromic features
Tags
  • early-onset