1. Genes and Genomic Entities
  2. HOXA11

HOXA11

homeobox A11
OMIM: 142958, Gene2Phenotype

8 panels

Panel Reviews Mode of inheritance Details
8 panels
Red HOXA11 in Limb disorders


Version 4.23
Latest signed off version: v4.0 (22 Mar 2023)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Red
    • Literature
    Phenotypes
    • Radioulnar synostosis with amegakaryocytic thrombocytopenia 1, OMIM:605432
    • radioulnar synostosis with amegakaryocytic thrombocytopenia 1, MONDO:0024558
    Green HOXA11 in Inherited bleeding disorders

    Level 3: Haemostasis disorders
    Level 2: Haematological and immunological disorders
    Version 1.178

    		review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Green
    • BRIDGE Study Tier 1 Gene
    Phenotypes
    • Amegakaryocytic thrombocytopenia with radioulnar synostosis
    Amber HOXA11 in Cytopenias and congenital anaemias

    Level 3: Anaemias and red cell disorders
    Level 2: Haematological disorders
    Version 1.118

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Amber
    • Expert list
    • Radboud University Medical Center, Nijmegen
    Phenotypes
    • Congenital amegkaryocytic thrombocytopenia
    • Radioulnar synostosis with amegakaryocytic thrombocytopenia, 605432
    Red HOXA11 in Skeletal dysplasia

    Level 3: Skeletal dysplasias
    Level 2: Skeletal disorders
    Version 4.65
    Latest signed off version: v4.0 (22 Mar 2023)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • NHS GMS
    • Expert Review Red
    • Expert list
    • UKGTN
    • Radboud University Medical Center, Nijmegen
    Phenotypes
    • Radioulnar synostosis with amegakaryocytic thrombocytopenia 1 605432
    Amber HOXA11 in Bleeding and platelet disorders


    Version 3.10
    Latest signed off version: v3.0 (22 Mar 2023)

    		review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Amber
    • North West GLH
    • Yorkshire and North East GLH
    • London South GLH
    • NHS GMS
    • Wessex and West Midlands GLH
    Phenotypes
    • 605432 Radioulnar synostosis with amegakaryocytic thrombocytopenia 1
    Red HOXA11 in Cytopenia - NOT Fanconi anaemia


    Version 3.34
    Latest signed off version: v3.0 (22 Mar 2023)

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Red
    • Expert review Red
    • North West GLH
    • Wessex and West Midlands GLH
    • Yorkshire and North East GLH
    • NHS GMS
    • London South GLH
    Phenotypes
    • Radioulnar synostosis with amegakaryocytic thrombocytopenia 1, 605432
    Red HOXA11 in DDG2P


    Version 3.90
    Latest signed off version: v3.1 (22 Mar 2023)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • DD-Gene2Phenotype
    • Expert Review Red
    Phenotypes
    • Radioulnar Synostosis with Amegakaryocytic Thrombocytopenia
    Green HOXA11 in Severe Paediatric Disorders


    Version 1.184

    		review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Next Generation Children Project
    • Expert Review Green
    • Expert list
    Phenotypes
    • Radioulnar synostosis with amegakaryocytic thrombocytopenia 1, 605432