1. Genes and Genomic Entities
  2. IFNGR1

IFNGR1

interferon gamma receptor 1
OMIM: 107470, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green IFNGR1 in COVID-19 research


Level 2: Viral research
Version 1.147

review BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • London North GLH
  • NHS GMS
  • GRID V2.0
  • Victorian Clinical Genetics Services
  • North West GLH
  • ESID Registry 20171117
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • Immunodeficiency 27A, (AR) 209950
  • Susceptibility to mycobacteria and Salmonella
  • Mycobacteriosis
  • Defects with susceptibility to mycobacterial infection (MSMD)
  • Defects in Intrinsic and Innate Immunity
  • Immunodeficiency 27B, (AD) 615978
Green IFNGR1 in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 8.85
Latest signed off version: v8.0 (30 Apr 2025)

review BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Sources
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • ESID Registry 20171117
  • GRID V2.0
Phenotypes
  • Immunodeficiency 27A, (AR) 209950
  • Immunodeficiency 27B, (AD) 615978
  • Mycobacteriosis
  • Defects with susceptibility to mycobacterial infection (MSMD)
  • Susceptibility to mycobacteria and Salmonella
  • Defects in Intrinsic and Innate Immunity