IKBKB

inhibitor of nuclear factor kappa B kinase subunit beta
OMIM: 603258, Gene2Phenotype

3 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 3 panels
Green IKBKB in COVID-19 research Level 2: Viral research Version 1.142	review	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 Phenotypes Immunodeficiency 15A, OMIM:618204 (AD) Immunodeficiency 15B, OMIM:615592 (AR) Combined immunodeficiency Recurrent bacterial, viral, fungal infections, opportunistic infections Immunodeficiencies affecting cellular and humoral immunity
Green IKBKB in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.202 Latest signed off version: v4.0 (22 Mar 2023)	review	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 Phenotypes Immunodeficiency 15A, OMIM:618204 (AD) Immunodeficiency 15B, OMIM:615592 (AR) Combined immunodeficiency Recurrent bacterial, viral, fungal infections, opportunistic infections Immunodeficiencies affecting cellular and humoral immunity
Green IKBKB in Severe Paediatric Disorders Version 1.184	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Immunodeficiency 15A, 618204 Immunodeficiency 15B, 615592