IL10RA

interleukin 10 receptor subunit alpha
OMIM: 146933, Gene2Phenotype

5 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 5 panels
Green IL10RA in Infantile enterocolitis & monogenic inflammatory bowel disease Level 3: Gastrointestinal disorders Level 2: Gastroenterological disorders Version 1.44	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen UKGTN Emory Genetics Laboratory Eligibility statement prior genetic testing Expert list Phenotypes IL-10 signalling defects / deficiency Inflammatory bowel disease 28, early onset, autosomal recessive 613148
Green IL10RA in Gastrointestinal epithelial barrier disorders Level 3: Gastrointestinal disorders Level 2: Gastroenterological disorders Version 1.75	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other UKGTN Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Emory Genetics Laboratory Phenotypes Early Onset Inflammatory Bowel Disease Inflammatory bowel disease 28, early onset, autosomal recessive, 613148 Inflammatory Bowel Disease Inflammatory Bowel Disease (Very Early Onset) IL-10 signalling defects / deficiency Inflammatory bowel disease 28, early onset, autosomal recessive 613148 Ulcerative Colitis
Green IL10RA in COVID-19 research Level 2: Viral research Version 1.142	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH GOSH PID v.8.0 NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Phenotypes IBD, Folliculitis, recurrent respiratory diseases, arthritis, lymphoma Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome Diseases of Immune Dysregulation Inflammatory bowel disease 28, early onset, autosomal recessive, 613148
Green IL10RA in Primary immunodeficiency or monogenic inflammatory bowel disease Version 5.3 Latest signed off version: v5.0 (1 May 2024)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Phenotypes Inflammatory bowel disease 28, early onset, autosomal recessive, 613148 Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome IBD, Folliculitis, recurrent respiratory diseases, arthritis, lymphoma Diseases of Immune Dysregulation Tags early-onset
Green IL10RA in Severe Paediatric Disorders Version 1.184	review	BIALLELIC, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Inflammatory bowel disease 28, early onset, autosomal recessive, 613148