IRAK4

interleukin 1 receptor associated kinase 4
OMIM: 606883, Gene2Phenotype

3 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 3 panels
Green IRAK4 in COVID-19 research Level 2: Viral research Version 1.142	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 Phenotypes Defects with susceptibility to mycobacterial infection (MSMD) Defects of TLR/NFkappa-B signalling Invasive pneumococcal disease, recurrent isolated, 1, 6107 IRAK4 deficiency, 610799 Defects in Intrinsic and Innate Immunity Bacterial infections (pyogens)
Green IRAK4 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.202 Latest signed off version: v4.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 Phenotypes IRAK4 deficiency, 610799 Invasive pneumococcal disease, recurrent isolated, 1, 6107 Defects of TLR/NFkappa-B signalling Defects with susceptibility to mycobacterial infection (MSMD) Bacterial infections (pyogens) Defects in Intrinsic and Innate Immunity
Green IRAK4 in Severe Paediatric Disorders Version 1.184	review	BIALLELIC, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Invasive pneumococcal disease, recurrent isolated, 1, 610799 IRAK4 deficiency, 607676