1. Genes and Genomic Entities
  2. IRF3

IRF3

interferon regulatory factor 3
OMIM: 603734, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green IRF3 in COVID-19 research


Level 2: Viral research
Version 1.146

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Expert list
  • IUIS Classification December 2019
  • IUIS Classification February 2018
Phenotypes
  • {Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 7}, 616532
  • {Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 7}, MIM616532
  • Herpes simplex virus 1 encephalitis
  • Defects in Intrinsic and Innate Immunity
Amber IRF3 in Primary immunodeficiency or monogenic inflammatory bowel disease


Level 2: Immunology
Version 8.78
Latest signed off version: v8.0 (30 Apr 2025)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • IUIS Classification December 2019
  • Expert Review Amber
  • IUIS Classification February 2018
Phenotypes
  • Defects in Intrinsic and Innate Immunity
  • {Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 7}, 616532
  • Herpes simplex virus 1 encephalitis