IRF8

interferon regulatory factor 8
OMIM: 601565, Gene2Phenotype

3 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 3 panels
Green IRF8 in COVID-19 research Level 2: Viral research Version 1.141	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 Literature Phenotypes Immunodeficiency 32B, monocyte and dendritic cell deficiency, autosomal recessive, 226990 Susceptibility to mycobacteria and multiple other infectious agents Immunodeficiency 32A, mycobacteriosis, autosomal dominant, 614893 Defects with susceptibility to mycobacterial infection (MSMD) Susceptibility to mycobacteria familial NK cell deficiency Defects in Intrinsic and Innate Immunity
Green IRF8 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.201 Latest signed off version: v4.0 (22 Mar 2023)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 Phenotypes Immunodeficiency 32A, mycobacteriosis, autosomal dominant, 614893 Immunodeficiency 32B, monocyte and dendritic cell deficiency, autosomal recessive, 226990 Defects with susceptibility to mycobacterial infection (MSMD) Susceptibility to mycobacteria Defects in Intrinsic and Innate Immunity Susceptibility to mycobacteria and multiple other infectious agents
Green IRF8 in Severe Paediatric Disorders Version 1.184	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Immunodeficiency 32B, monocyte and dendritic cell deficiency, autosomal recessive, 226990 Immunodeficiency 32A, mycobacteriosis, autosomal dominant, 614893