1. Genes and Genomic Entities
  2. ITSN1

ITSN1

intersectin 1
OMIM: 602442, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green ITSN1 in Intellectual disability


Level 2: Developmental disorders
Version 10.17
Latest signed off version: v10.0 (6 May 2026)

Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • NHS GMS
    • Literature
    Phenotypes
    • neurodevelopmental disorder, MONDO:0700092
    • intellectual disability, MONDO:0001071
    Tags
    • gene-checked
    Green ITSN1 in Proteinuric renal disease


    Level 2: Renal
    Version 6.1
    Latest signed off version: v6.0 (6 May 2026)

    Component of the following Super Panels:

  • Unexplained young onset end-stage renal disease

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    Phenotypes
    • Early childhood SSNS
    Tags
    • gene-checked