IYD

iodotyrosine deiodinase
OMIM: 612025, Gene2Phenotype

1 panel

Panel Reviews Mode of inheritance Details
1 panel

Green IYD in Congenital hypothyroidism

Level 3: Thyroid disorders
Level 2: Endocrine disorders
Version 2.5
Latest signed off version: v2.2 (25 Feb 2020)

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Other
  • Illumina TruGenome Clinical Sequencing Services
Phenotypes
  • Congenital hypothyroidism
  • Thyroid dyshormonogenesis 4, 274800
  • goitre
  • childhood/adolescent onset hypothyroidism
  • normal iodide organification
  • raised urinary MIT and DIT