1. Genes and Genomic Entities
  2. KLF8

KLF8

Kruppel like factor 8
OMIM: 300286, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Red KLF8 in DDG2P


Version 8.1
Latest signed off version: v8.0 (12 Aug 2026)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
    Sources
    • DD-Gene2Phenotype
    • Expert Review Red
    Phenotypes
    • NONSYNDROMIC MENTAL RETARDATION
    Red KLF8 in Intellectual disability


    Level 2: Developmental disorders
    Version 11.17
    Latest signed off version: v11.0 (12 Aug 2026)

    Component of the following Super Panels:

  • Hypotonic infant
  • Leukodystrophy, childhood onset
  • Paediatric disorders

    		•  review X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
    Sources
    • Expert Review Red
    • Emory Genetics Laboratory
    Phenotypes
    • Intellectual disability