KRT10

keratin 10
OMIM: 148080, Gene2Phenotype

8 panels

Panel Reviews Mode of inheritance Details
8 panels
Green KRT10 in Palmoplantar keratoderma and erythrokeratodermas

Level 3: Keratodermas
Level 2: Dermatological disorders
Version 1.31

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Other
Phenotypes
  • ichthyosis with confetti, 609165
  • erythroderma, prominent scale, and palmoplantar keratoderma
  • Epidermolytic hyperkeratosis (EHK), 113800
  • Ichthyosis, cyclic, with epidermolytic hyperkeratosis, 607602
Red KRT10 in Peeling skin syndrome

Level 3: Skin fragility disorders
Level 2: Dermatological disorders
Version 1.4

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Other
Phenotypes
  • Epidermolytic hyperkeratosis, 113800
  • EHK
Green KRT10 in Ichthyosis and erythrokeratoderma


Version 3.22
Latest signed off version: v3.2 (22 Mar 2023)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
Phenotypes
  • Epidermolytic hyperkeratosis (EHK), OMIM:113800
  • ichthyosis with confetti, OMIM:609165
  • Ichthyosis, cyclic, with epidermolytic hyperkeratosis, OMIM:607602
Green KRT10 in Epidermolysis bullosa and congenital skin fragility


Version 2.7
Latest signed off version: v2.2 (22 Mar 2023)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
Phenotypes
  • Epidermolytic hyperkeratosis, OMIM:113800
Green KRT10 in Palmoplantar keratodermas


Version 3.24
Latest signed off version: v3.0 (22 Mar 2023)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • London North GLH
  • NHS GMS
  • Expert Review Green
Phenotypes
  • Pachyonychia congenita
  • Palmoplantar keratoderma
  • Ichythosis with confetti
  • Epidermolytic hyperkeratosis
Green KRT10 in Pigmentary skin disorders


Version 3.10
Latest signed off version: v3.0 (22 Mar 2023)

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • London North GLH
  • NHS GMS
  • Expert Review Green
Phenotypes
  • CRIE
  • Ichythosis with confetti
  • Pachyonychia congenita
  • Palmoplantar keratoderma
  • Epidermolytic hyperkeratosis
  • ERYTHRODERMA, ICHTHYOSIFORM, CONGENITAL RETICULAR
Amber KRT10 in Rare genetic inflammatory skin disorders


Version 3.5
Latest signed off version: v3.0 (22 Mar 2023)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Amber
  • London North GLH
  • NHS GMS
Phenotypes
  • Ichythosis with confetti
  • Pachyonychia congenita
  • Palmoplantar keratoderma
  • Epidermolytic hyperkeratosis
Green KRT10 in Mosaic skin disorders - deep sequencing


Version 2.41
Latest signed off version: v2.0 (30 Nov 2022)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • London North GLH
  • NHS GMS
  • Expert Review Green
Phenotypes
  • Epidermolytic hyperkeratosis
  • Palmoplantar keratoderma
  • Ichythosis with confetti
  • Pachyonychia congenita