LAMC2

laminin subunit gamma 2
OMIM: 150292, Gene2Phenotype

4 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 4 panels
Green LAMC2 in Epidermolysis bullosa Level 3: Skin fragility disorders Level 2: Dermatological disorders Version 1.12	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Eligibility statement prior genetic testing Phenotypes Epidermolysis bullosa, junctional, Herlitz type, 226700 Epidermolysis bullosa, junctional, non-Herlitz type, 226650 Junctional Epidermolysis Bullosa Severe generalised junctional Epidermolysis bullosa (occasionally intermediate)
Green LAMC2 in Epidermolysis bullosa and congenital skin fragility Level 2: Dermatology Version 2.13 Latest signed off version: v2.2 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Phenotypes Epidermolysis bullosa, junctional, Herlitz type, OMIM:226700 Epidermolysis bullosa, junctional, non-Herlitz type, OMIM:226650
Amber LAMC2 in Amelogenesis imperfecta Level 2: Musculoskeletal Version 4.30 Latest signed off version: v4.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Amber UKGTN Eligibility statement prior genetic testing Phenotypes amelogenesis imperfecta, MONDO:0019507 Tags watchlist
Red LAMC2 in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.140 Latest signed off version: v6.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red PAGE Additional Gene List Phenotypes Epidermolysis bullosa, junctional 226700 Epidermolysis bullosa, junctional 226650