LAT

linker for activation of T-cells
OMIM: 602354, Gene2Phenotype

5 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 5 panels
Green LAT in COVID-19 research Level 2: Viral research Version 1.146	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 SCID v1.6 A- or hypo-gammaglobulinaemia v1.25 London North GLH NHS GMS North West GLH Combined B and T cell defect v1.12 Expert Review Green NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 SCID v1.6 Combined B and T cell defect v1.12 A- or hypo-gammaglobulinaemia v1.25 Phenotypes Immunodeficiencies affecting cellular and humoral immunity Immunodeficiency 52, 617514 Adenopathy, splenomegaly, recurrent infections, autoimmunity
Amber LAT in Inherited bleeding disorders Level 3: Haemostasis disorders Level 2: Haematological and immunological disorders Version 1.182	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Other Phenotypes Immunodeficiency 52, 617514 Tags watchlist
Green LAT in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.78 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 SCID v1.6 Combined B and T cell defect v1.12 A- or hypo-gammaglobulinaemia v1.25 Phenotypes Immunodeficiency 52, 617514 Adenopathy, splenomegaly, recurrent infections, autoimmunity Immunodeficiencies affecting cellular and humoral immunity
Amber LAT in Cytopenias and congenital anaemias Level 3: Anaemias and red cell disorders Level 2: Haematological disorders Version 1.123	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Other Phenotypes Immunodeficiency 52, 617514 Tags watchlist
Amber LAT in Cytopenia - NOT Fanconi anaemia Level 2: Haematology Version 4.32 Latest signed off version: v4.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources North West GLH NHS GMS Expert Review Amber Wessex and West Midlands GLH Phenotypes Immunodeficiency 52, 617514