MAP3K14

mitogen-activated protein kinase kinase kinase 14
OMIM: 604655, Gene2Phenotype

2 panels

Panel	Reviews	Mode of inheritance	Details
Green MAP3K14 in COVID-19 research Level 2: Viral research Version 1.146	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 North West GLH Victorian Clinical Genetics Services Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green GRID V2.0 Phenotypes Low NK number and function, recurrent bacterial, viral and Cryptosporidium infections Recessive Atypical Combined Immunodeficiency Primary Immunodeficiency with Multifaceted Aberrant Lymphoid Immunity Immunodeficiencies affecting cellular and humoral immunity Immunodeficiency 112, OMIM:620449
Green MAP3K14 in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.78 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services GRID V2.0 Phenotypes Immunodeficiency 112, OMIM:620449

Panel

Reviews

Mode of inheritance

Details

Level 2: Viral research
Version 1.146

review

BIALLELIC, autosomal or pseudoautosomal

Low NK number and function, recurrent bacterial, viral and Cryptosporidium infections
Recessive Atypical Combined Immunodeficiency
Primary Immunodeficiency with Multifaceted Aberrant Lymphoid Immunity
Immunodeficiencies affecting cellular and humoral immunity
Immunodeficiency 112, OMIM:620449

Level 2: Immunology
Version 8.78
Latest signed off version: v8.0 (30 Apr 2025)

review

BIALLELIC, autosomal or pseudoautosomal