MARS

methionyl-tRNA synthetase
OMIM: 156560, Gene2Phenotype

10 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 10 panels
Red MARS in Xeroderma pigmentosum, Trichothiodystrophy or Cockayne syndrome Level 2: Dermatology Version 3.7 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Red Literature Phenotypes trichothiodystrophy, MONDO:0018053 Tags new-gene-name watchlist
Amber MARS in Adult onset leukodystrophy Level 2: Neurology Version 6.10 Latest signed off version: v6.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Amber NHS GMS Yorkshire and North East GLH Phenotypes Charcot-Marie-Tooth disease, axonal, type 2U, 616280 Tags new-gene-name
Red MARS in Hereditary spastic paraplegia Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.316	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red Expert list Tags new-gene-name
Red MARS in Childhood onset hereditary spastic paraplegia Level 2: Neurology Version 8.53 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Yorkshire and North East GLH Expert Review Red Expert list Tags new-gene-name
Red MARS in Adult onset hereditary spastic paraplegia Level 2: Neurology Version 6.9 Latest signed off version: v6.0 (30 Apr 2025) Component of the following Super Panels: Adult-onset neurological disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Yorkshire and North East GLH South West GLH Tags new-gene-name
Red MARS in Adult onset neurodegenerative disorder Level 2: Neurology Version 8.21 Latest signed off version: v8.0 (30 Apr 2025) Component of the following Super Panels: Adult-onset neurological disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Yorkshire and North East GLH Expert Review Red Tags new-gene-name
Red MARS in Hereditary neuropathy Level 3: Motor and Sensory Disorders of the PNS Level 2: Neurology and neurodevelopmental disorders Version 1.508	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources South West GLH NHS GMS London North GLH Expert Review Red Expert Review Phenotypes Charcot-Marie-Tooth disease, axonal, type 2U, 616280 Tags new-gene-name
Red MARS in Hereditary neuropathy or pain disorder Level 2: Neurology Version 7.45 Latest signed off version: v7.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Expert Review Red South West GLH London North GLH NHS GMS South West GLH NHS GMS London North GLH Phenotypes Charcot-Marie-Tooth disease, axonal, type 2U, 616280 Tags new-gene-name
Green MARS in Pulmonary fibrosis familial Level 2: Respiratory Version 1.9 Latest signed off version: v1.3 (30 Nov 2022)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Phenotypes Interstitial lung and liver disease, OMIM:615486 Tags new-gene-name
Green MARS in Childhood interstitial lung disease Level 2: Respiratory Version 0.9	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Phenotypes severe early-onset pulmonary alveolar proteinosis due to MARS deficiency, MONDO:0014206 Interstitial lung and liver disease, OMIM:615486 Tags new-gene-name