MARS

methionyl-tRNA synthetase
OMIM: 156560, Gene2Phenotype

7 panels

Panel Reviews Mode of inheritance Details
7 panels

Green MARS in White matter disorders - adult onset


Version 1.7
Signed off v.1.6 on 15 Oct 2020

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • NHS GMS
  • Yorkshire and North East GLH
Phenotypes
  • Charcot-Marie-Tooth disease, axonal, type 2U, 616280
Tags
  • new-gene-name

Red MARS in Hereditary spastic paraplegia

Level 3: Motor Disorders of the CNS
Level 2: Neurology and neurodevelopmental disorders
Version 1.219

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Red
  • Expert list
Tags
  • new-gene-name

Red MARS in Hereditary spastic paraplegia - childhood onset


Version 2.25
Signed off v.2.18 on 8 Oct 2020

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • Yorkshire and North East GLH
  • Expert Review Red
  • Expert list
Tags
  • new-gene-name

Red MARS in Hereditary spastic paraplegia - adult onset


Version 1.16
Signed off v.1.12 on 15 Oct 2020

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • Yorkshire and North East GLH
  • South West GLH
Tags
  • new-gene-name

Red MARS in Neurodegenerative disorders - adult onset


Version 2.38
Signed off v.2.31 on 8 Oct 2020

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • Yorkshire and North East GLH
  • Expert Review Red
Tags
  • new-gene-name

Red MARS in Hereditary neuropathy

Level 3: Motor and Sensory Disorders of the PNS
Level 2: Neurology and neurodevelopmental disorders
Version 1.383

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • South West GLH
  • NHS GMS
  • London North GLH
  • Expert Review Red
  • Expert Review
Phenotypes
  • Charcot-Marie-Tooth disease, axonal, type 2U, 616280
Tags
  • new-gene-name

Red MARS in Hereditary neuropathy NOT PMP22 copy number


Version 1.21
Signed off v.1.2 on 27 Feb 2020

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review
  • Expert Review Red
  • South West GLH
  • London North GLH
  • NHS GMS
  • South West GLH
  • NHS GMS
  • London North GLH
Phenotypes
  • Charcot-Marie-Tooth disease, axonal, type 2U, 616280