1. Genes and Genomic Entities
  2. MEIS2

MEIS2

Meis homeobox 2
OMIM: 601740, Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels
Green MEIS2 in Fetal anomalies


Version 3.169
Latest signed off version: v3.0 (22 Mar 2023)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Cleft palate, cardiac defects, and mental retardation, OMIM:600987
  • Cardiac malformation, cleft lip/palate, microcephaly, and digital anomalies, MONDO:0010970
Green MEIS2 in DDG2P


Version 3.90
Latest signed off version: v3.1 (22 Mar 2023)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • MEIS2-related developmental disorder (monoallelic)
    Green MEIS2 in Clefting

    Level 3: Dysmorphic disorders
    Level 2: Dysmorphic and congenital abnormality syndromes
    Version 4.111
    Latest signed off version: v4.0 (22 Mar 2023)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green
    • Expert Review
    Phenotypes
    • Cleft palate, cardiac defects, and mental retardation, OMIM:600987
    • Cardiac malformation, cleft lip/palate, microcephaly, and digital anomalies, MONDO:0010970
    Green MEIS2 in Intellectual disability - microarray and sequencing

    Level 3: Neurodevelopmental disorders
    Level 2: Neurology and neurodevelopmental disorders
    Version 5.557
    Latest signed off version: v5.0 (22 Mar 2023)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    • Literature
    Phenotypes
    • Cleft palate, cardiac defects, and mental retardation, OMIM:600987
    • Cardiac malformation, cleft lip/palate, microcephaly, and digital anomalies, MONDO:0010970
    Green MEIS2 in Severe Paediatric Disorders


    Version 1.184

    		review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Next Generation Children Project
    • Expert Review Green
    • Expert list
    Phenotypes
    • Cleft palate, cardiac defects, and mental retardation, OMIM:600987
    • Cardiac malformation, cleft lip/palate, microcephaly, and digital anomalies, MONDO:0010970