1. Genes and Genomic Entities
  2. NAF1

NAF1

nuclear assembly factor 1 ribonucleoprotein
Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Green NAF1 in Haematological malignancies for rare disease

Level 3: Tumour syndromes
Level 2: Tumour syndromes
Version 1.19

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Curated sources
  • Expert Review Green
Phenotypes
  • Class: BM failure syndrome (typ AR)
  • Dyskeratosis congenita
  • MDS, AML
  • Oral and GI squamous cell carcinoma
Green NAF1 in Haematological malignancies cancer susceptibility


Level 2: Cancer susceptibility
Version 5.1
Latest signed off version: v5.0 (6 May 2026)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Curated sources
Phenotypes
  • Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 7, OMIM:620365
  • Class: BM failure syndrome (typ AR)
  • Dyskeratosis congenita
  • MDS, AML
  • Oral and GI squamous cell carcinoma
Green NAF1 in Pulmonary fibrosis familial


Level 2: Respiratory
Version 1.10
Latest signed off version: v1.9 (6 May 2026)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
Phenotypes
  • Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 7, OMIM:620365
  • pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 7, MONDO:0957261
Green NAF1 in Childhood interstitial lung disease


Level 2: Respiratory
Version 1.1
Latest signed off version: v1.0 (6 May 2026)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • NHS GMS
Phenotypes
  • pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 7, MONDO:0957261
  • Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 7, OMIM:620365