NECTIN1

nectin cell adhesion molecule 1
OMIM: 600644, Gene2Phenotype

7 panels

Panel Reviews Mode of inheritance Details
7 panels
Amber NECTIN1 in COVID-19 research


Level 2: Viral research
Version 1.147

review Unknown
Sources
  • Expert Review Amber
  • OMIM
  • Expert list
Green NECTIN1 in Ectodermal dysplasia


Level 2: Dermatology
Version 4.27
Latest signed off version: v4.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
Phenotypes
  • Cleft lip/palate-ectodermal dysplasia syndrome, 225060
  • Orofacial cleft 7, 225060
Green NECTIN1 in Ectodermal dysplasia without a known gene mutation

Level 3: Ectodermal dysplasias
Level 2: Dermatological disorders
Version 1.30

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Illumina TruGenome Clinical Sequencing Services
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Cleft lip/palate-ectodermal dysplasia syndrome, 225060
  • Orofacial cleft 7, 225060
Green NECTIN1 in Fetal anomalies


Level 2: Fetal (including NIPD)
Version 6.185
Latest signed off version: v6.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Cleft lip/palate-ectodermal dysplasia syndrome, OMIM:225060
  • Orofacial cleft 7, OMIM:225060
Green NECTIN1 in DDG2P


Version 6.447
Latest signed off version: v6.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • DD-Gene2Phenotype
    Phenotypes
    • NECTIN1-related cleft lip/palate-ectodermal dysplasia syndrome, OMIM:225060
    Green NECTIN1 in Clefting


    Level 2: Musculoskeletal
    Version 6.23
    Latest signed off version: v6.5 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green
    • Illumina TruGenome Clinical Sequencing Services
    • Radboud University Medical Center, Nijmegen
    Phenotypes
    • Cleft lip/Palate ectodermal dysplasia syndrome, 225060
    • Orofacial cleft 7, 225060
    • Cleft Lip with or without Cleft Palate
    • Zlotogora-Ogur syndrome
    • CLP, partial syndactyly of digits, intellectual disability, dysmorphism
    • Ectodermal dysplasia, Margarita Island type
    • Cleft lip
    Red NECTIN1 in Intellectual disability


    Level 2: Developmental disorders
    Version 9.370
    Latest signed off version: v9.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders
  • review Not set
    Sources
    • Expert Review Red
    • Radboud University Medical Center, Nijmegen
    Phenotypes
    • Cleft lip/palate-ectodermal dysplasia syndrome, 225060Orofacial cleft 7, 225060
    • CLEFT LIP/PALATE-ECTODERMAL DYSPLASIA SYNDROME