NECTIN4

nectin cell adhesion molecule 4
OMIM: 609607, Gene2Phenotype

6 panels

Panel Reviews Mode of inheritance Details
6 panels
Green NECTIN4 in Ectodermal dysplasia


Level 2: Dermatology
Version 4.23
Latest signed off version: v4.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
Phenotypes
  • Ectodermal dysplasia-syndactyly syndrome 1, OMIM:613573
  • ectodermal dysplasia-syndactyly syndrome 1, MONDO:0024565
Green NECTIN4 in Ectodermal dysplasia without a known gene mutation

Level 3: Ectodermal dysplasias
Level 2: Dermatological disorders
Version 1.30

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Ectodermal dysplasia-syndactyly syndrome 1, OMIM:613573
Amber NECTIN4 in Palmoplantar keratodermas


Level 2: Dermatology
Version 4.9
Latest signed off version: v4.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • Other
Phenotypes
  • Ectodermal dysplasia-syndactyly syndrome 1, OMIM:613573
  • ectodermal dysplasia-syndactyly syndrome 1, MONDO:0024565
Tags
  • Q4_25_promote_green
Amber NECTIN4 in Amelogenesis imperfecta


Level 2: Musculoskeletal
Version 4.26
Latest signed off version: v4.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • Literature
Phenotypes
  • Ectodermal dysplasia-syndactyly syndrome 1, OMIM:613573
  • ectodermal dysplasia-syndactyly syndrome 1, MONDO:0024565
  • amelogenesis imperfecta, MONDO:0019507
Tags
  • Q4_25_promote_green
Green NECTIN4 in Fetal anomalies


Level 2: Fetal (including NIPD)
Version 6.140
Latest signed off version: v6.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • PAGE DD-Gene2Phenotype
  • Expert Review Green
Phenotypes
  • ECTODERMAL DYSPLASIA-SYNDACTYLY SYNDROME 1
Green NECTIN4 in DDG2P


Version 6.424
Latest signed off version: v6.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • ECTODERMAL DYSPLASIA-SYNDACTYLY SYNDROME 1 613573