1. Genes and Genomic Entities
  2. NLGN4X

NLGN4X

neuroligin 4, X-linked
OMIM: 300427, Gene2Phenotype

2 panels

Panel Reviews Mode of inheritance Details
2 panels
Green NLGN4X in DDG2P


Version 6.424
Latest signed off version: v6.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
    Sources
    • Expert Review Green
    • DD-Gene2Phenotype
    Phenotypes
    • SUSCEPTIBILITY TO AUTISM X-LINKED TYPE 2 300495
    Red NLGN4X in Intellectual disability


    Level 2: Developmental disorders
    Version 9.285
    Latest signed off version: v9.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review X-LINKED: hemizygous mutation in males, biallelic mutations in females
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Red
    • Emory Genetics Laboratory
    Phenotypes
    • SUSCEPTIBILITY TO AUTISM X-LINKED TYPE 2 (AUTSX2)