NLRC4

NLR family CARD domain containing 4
OMIM: 606831, Gene2Phenotype

6 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 6 panels
Red NLRC4 in Periodic fever syndromes Level 3: Multi-system inflammatory/autoimmune disorders Level 2: Rheumatological disorders Version 1.33	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red Other Phenotypes Autoinflammation with infantile enterocolitis, OMIM:616050 ?Familial cold autoinflammatory syndrome 4, OMIM:616115
Red NLRC4 in Gastrointestinal epithelial barrier disorders Level 3: Gastrointestinal disorders Level 2: Gastroenterological disorders Version 1.75	review	Not set	Sources Radboud University Medical Center, Nijmegen Phenotypes Autoinflammation with infantile enterocolitis, OMIM:616050
Green NLRC4 in COVID-19 research Level 2: Viral research Version 1.142	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 North West GLH Victorian Clinical Genetics Services Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green GRID V2.0 Phenotypes Autoinflammation with infantile enterocolitis, OMIM:616050 ?Familial cold autoinflammatory syndrome 4, OMIM:616115 Severe enterocolitis and macrophage activation syndrome Autoinflammatory Disorders
Green NLRC4 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 5.1 Latest signed off version: v5.0 (1 May 2024)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services GRID V2.0 Phenotypes Autoinflammation with infantile enterocolitis, OMIM:616050 ?Familial cold autoinflammatory syndrome 4, OMIM:616115 Severe enterocolitis and macrophage activation syndrome Autoinflammatory Disorders
Green NLRC4 in Severe Paediatric Disorders Version 1.184	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Autoinflammation with infantile enterocolitis, OMIM:616050 ?Familial cold autoinflammatory syndrome 4, OMIM:616115
Green NLRC4 in Autoinflammatory disorders Level 3: Primary immunodeficiency disorders Level 2: Haematological disorders Version 2.1 Latest signed off version: v2.0 (1 May 2024)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources NHS GMS Expert Review Green Phenotypes Autoinflammation with infantile enterocolitis, OMIM:616050 ?Familial cold autoinflammatory syndrome 4, OMIM:616115