NLRP12

NLR family pyrin domain containing 12
OMIM: 609648, Gene2Phenotype

6 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 6 panels
Green NLRP12 in Periodic fever syndromes Level 3: Multi-system inflammatory/autoimmune disorders Level 2: Rheumatological disorders Version 1.33	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Eligibility statement prior genetic testing Phenotypes Familial cold autoinflammatory syndrome 2, OMIM:611762
Green NLRP12 in COVID-19 research Level 2: Viral research Version 1.141	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 North West GLH Victorian Clinical Genetics Services Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green GRID V2.0 Phenotypes Familial cold autoinflammatory syndrome 2, OMIM:611762 Non-pruritic urticaria, arthritis, chills, fever and leukocytosis after cold exposure Preterm premature rupture of membranes (PPROM) Autoinflammatory Disorders
Green NLRP12 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.201 Latest signed off version: v4.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services GRID V2.0 Phenotypes Familial cold autoinflammatory syndrome 2, OMIM:611762 Non-pruritic urticaria, arthritis, chills, fever and leukocytosis after cold exposure Preterm premature rupture of membranes (PPROM) Autoinflammatory Disorders
Amber NLRP12 in Monogenic hearing loss Level 3: Non-syndromic hearing loss Level 2: Hearing and ear disorders Version 4.38 Latest signed off version: v4.0 (22 Mar 2023) Component of the following Super Panels: Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Amber Literature Phenotypes Familial cold autoinflammatory syndrome 2, OMIM:611762 sensorineural hearing loss disorder, MONDO:0020678 Tags Q2_24_promote_green
Green NLRP12 in Severe Paediatric Disorders Version 1.184	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Familial cold autoinflammatory syndrome 2, OMIM:611762
Green NLRP12 in Autoinflammatory disorders Level 3: Primary immunodeficiency disorders Level 2: Haematological disorders Version 1.17 Latest signed off version: v1.0 (30 Nov 2022)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources NHS GMS Expert Review Green Phenotypes Familial cold autoinflammatory syndrome 2, OMIM:611762