NTRK2

neurotrophic receptor tyrosine kinase 2
OMIM: 600456, Gene2Phenotype

9 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 9 panels
Red NTRK2 in Kleine-Levin syndrome Level 3: Sleep disorders Level 2: Neurology and neurodevelopmental disorders Version 1.8	review	Unknown	Sources Expert Review Red Emory Genetics Laboratory Phenotypes Obesity, hyperphagia, and developmental delay, 613886
Green NTRK2 in Severe early-onset obesity Level 2: Endocrinology Version 5.21 Latest signed off version: v5.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert list Expert Review Green Emory Genetics Laboratory Radboud University Medical Center, Nijmegen Phenotypes Obesity, hyperphagia, and developmental delay, OMIM:613886
Red NTRK2 in Paroxysmal central nervous system disorders Level 2: Neurology Version 4.2 Latest signed off version: v4.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Red NHS GMS London North GLH Wessex and West Midlands GLH Phenotypes Obesity, hyperphagia, and developmental delay, 613886 Epileptic encephalopathy, early infantile, 58, 617830
Amber NTRK2 in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.158 Latest signed off version: v6.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Amber PAGE DD-Gene2Phenotype Phenotypes Epilepsy and intellectual disability
Red NTRK2 in Rare syndromic craniosynostosis or isolated multisuture synostosis Level 2: Musculoskeletal Version 6.4 Latest signed off version: v6.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Literature Phenotypes Obesity, hyperphagia, and developmental delay, OMIM:613886 craniosynostosis, MONDO:0015469
Green NTRK2 in DDG2P Version 6.427 Latest signed off version: v6.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green DD-Gene2Phenotype Phenotypes Epilepsy and intellectual disability
Red NTRK2 in Monogenic hearing loss Level 2: Audiology Version 5.57 Latest signed off version: v5.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	Not set	Sources Expert
Green NTRK2 in Early onset or syndromic epilepsy Level 2: Neurology Version 8.158 Latest signed off version: v8.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders Unexplained death in infancy and sudden unexplained death in childhood	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Wessex and West Midlands GLH NHS GMS Expert Review Green Literature Phenotypes Epileptic encephalopathy, early infantile, 58 (MIM 617830) Obesity, hyperphagia, and developmental delay (MIM 613886)
Green NTRK2 in Intellectual disability Level 2: Developmental disorders Version 9.325 Latest signed off version: v9.0 (30 Apr 2025) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green Radboud University Medical Center, Nijmegen Literature Phenotypes Epileptic encephalopathy, early infantile, 58, 617830 Obesity, hyperphagia, and developmental delay, 613886