PLAT

plasminogen activator, tissue type
OMIM: 173370, Gene2Phenotype

3 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 3 panels
Green PLAT in Inherited bleeding disorders Level 3: Haemostasis disorders Level 2: Haematological and immunological disorders Version 1.182	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Eligibility statement prior genetic testing Other Expert Review Green BRIDGE Study Tier 1 Gene Phenotypes Tissue Plasminogen Activator deficiency Thrombophilia, familial, due to decreased release of PLAT 612348 Thrombophilia due to decreased release of tissue plasminogen
Amber PLAT in Thrombophilia with a likely monogenic cause Level 2: Haematology Version 2.10 Latest signed off version: v2.2 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Wessex and West Midlands GLH North West GLH Yorkshire and North East GLH NHS GMS London South GLH Phenotypes Thrombophilia, familial, due to decreased release of PLAT, OMIM:612348
Amber PLAT in Intellectual disability Level 2: Developmental disorders Version 9.285 Latest signed off version: v9.0 (30 Apr 2025) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber Literature Phenotypes neurodevelopmental disorder, MONDO:0700092 intellectual disability, MONDO:0001071