PLG

plasminogen
OMIM: 173350, Gene2Phenotype

8 panels

Panel Reviews Mode of inheritance Details
8 panels

Red PLG in Genomic imprinting


Version 0.104

review MONOALLELIC, autosomal or pseudoautosomal, maternally imprinted (paternal allele expressed)
Sources
  • Literature

Red PLG in COVID-19 research


Level 2: Viral research
Version 1.79

review Unknown
Sources
  • Literature

Green PLG in Hydrocephalus


Version 2.116
Latest signed off version: v2.3 (2 Mar 2020)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • Expert Review Green
  • Literature
Phenotypes
  • Plasminogen deficiency, type I, OMIM:217090
  • Dysplasminogenemia, OMIM:217090

Green PLG in Inherited bleeding disorders

Level 3: Haemostasis disorders
Level 2: Haematological and immunological disorders
Version 1.164

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Eligibility statement prior genetic testing
  • Expert Review Green
  • BRIDGE Study Tier 1 Gene
Phenotypes
  • Plasminogen deficiency, type I, OMIM:217090
  • Dysplasminogenemia, OMIM:217090

Amber PLG in Primary immunodeficiency


Version 2.465
Latest signed off version: v2.1 (24 Feb 2020)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Amber
  • Literature
Phenotypes
  • Angioedema, hereditary, 4, OMIM:619360
Tags
  • Q2_21_NHS_review
  • Q3_21_expert_review

Green PLG in Thrombophilia


Version 1.20
Latest signed off version: v1.2 (3 Mar 2020)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • North West GLH
  • Yorkshire and North East GLH
  • London South GLH
  • NHS GMS
  • Expert Review Green
  • Wessex and West Midlands GLH
Phenotypes
  • Plasminogen deficiency, type I, OMIM:217090
  • Dysplasminogenemia, OMIM:217090

Amber PLG in Fetal anomalies


Version 1.717
Latest signed off version: v1.92 (21 Aug 2020)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Amber
  • Expert list
Phenotypes
  • Plasminogen deficiency, type I, OMIM:217090
  • Dysplasminogenemia, OMIM:217090
Tags
  • for-review

Green PLG in Severe Paediatric Disorders


Version 1.84

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Plasminogen deficiency, type I, 217090
  • Dysplasminogenemia, 217090