PRKDC

Green PRKDC in COVID-19 research

Level 2: Viral research
Version 1.142

Sources

• IUIS Classification February 2018
• SCID v1.6
• London North GLH
• GOSH PID v.8.0
• NHS GMS
• GRID V2.0
• Victorian Clinical Genetics Services
• North West GLH
• ESID Registry 20171117
• Expert Review Green
• NHS GMS
• North West GLH
• London North GLH
• IUIS Classification February 2018
• Victorian Clinical Genetics Services
• Expert Review Green
• ESID Registry 20171117
• GRID V2.0
• GOSH PID v.8.0
• SCID v1.6

Phenotypes

• Immunodeficiency 26, with or without neurologic abnormalities
• DNA Pkcs deficiency
• Combined immunodeficiency
• Immunodeficiency, with or without neurologic abnormalities
• Nl NK, radiation sensitive, microcephaly
• Immunodeficiencies affecting cellular and humoral immunity
• Severe combined immunodeficiency (SCID)

Green PRKDC in Primary immunodeficiency or monogenic inflammatory bowel disease

Version 4.202
Latest signed off version: v4.0 (22 Mar 2023)

Sources

• NHS GMS
• North West GLH
• London North GLH
• IUIS Classification February 2018
• Victorian Clinical Genetics Services
• Expert Review Green
• ESID Registry 20171117
• GRID V2.0
• GOSH PID v.8.0
• SCID v1.6

Phenotypes

• Immunodeficiency 26, with or without neurologic abnormalities
• Immunodeficiency, with or without neurologic abnormalities
• DNA Pkcs deficiency
• Combined immunodeficiency
• Severe combined immunodeficiency (SCID)
• Nl NK, radiation sensitive, microcephaly
• Immunodeficiencies affecting cellular and humoral immunity

Red PRKDC in Autism

Version 0.36

Sources

• Expert Review Red
• SFARI

Green PRKDC in Severe Paediatric Disorders

Version 1.184

Sources

• Next Generation Children Project
• Expert Review Green
• Expert list

Phenotypes

• Immunodeficiency 26, with or without neurologic abnormalities, 615966